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Conditional prediction of consecutive tumor evolution using cancer progression models: What genotype comes next?

Accurate prediction of tumor progression is key for adaptive therapy and precision medicine. Cancer progression models (CPMs) can be used to infer dependencies in mutation accumulation from cross-sectional data and provide predictions of tumor progression paths. However, their performance when predi...

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Detalles Bibliográficos
Autores principales: Diaz-Colunga, Juan, Diaz-Uriarte, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730404/
https://www.ncbi.nlm.nih.gov/pubmed/34932572
http://dx.doi.org/10.1371/journal.pcbi.1009055