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A hybrid stochastic-deterministic approach to explore multiple infection and evolution in HIV

To study viral evolutionary processes within patients, mathematical models have been instrumental. Yet, the need for stochastic simulations of minority mutant dynamics can pose computational challenges, especially in heterogeneous systems where very large and very small sub-populations coexist. Here...

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Detalles Bibliográficos
Autores principales: Kreger, Jesse, Komarova, Natalia L., Wodarz, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730440/
https://www.ncbi.nlm.nih.gov/pubmed/34936647
http://dx.doi.org/10.1371/journal.pcbi.1009713