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A hybrid stochastic-deterministic approach to explore multiple infection and evolution in HIV
To study viral evolutionary processes within patients, mathematical models have been instrumental. Yet, the need for stochastic simulations of minority mutant dynamics can pose computational challenges, especially in heterogeneous systems where very large and very small sub-populations coexist. Here...
Autores principales: | Kreger, Jesse, Komarova, Natalia L., Wodarz, Dominik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730440/ https://www.ncbi.nlm.nih.gov/pubmed/34936647 http://dx.doi.org/10.1371/journal.pcbi.1009713 |
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