Discovery of highly potent SARS-CoV-2 M(pro) inhibitors based on benzoisothiazolone scaffold

The COVID-19 pandemic has drastically impacted global economies and public health. Although vaccine development has been successful, it was not sufficient against more infectious mutant strains including the Delta variant indicating a need for alternative treatment strategies such as small molecular...

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Detalles Bibliográficos
Autores principales: Chen, Weixiong, Feng, Bo, Han, Sheng, Wang, Peipei, Chen, Wuhong, Zang, Yi, Li, Jia, Hu, Youhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730469/
https://www.ncbi.nlm.nih.gov/pubmed/34998903
http://dx.doi.org/10.1016/j.bmcl.2022.128526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730469/
https://www.ncbi.nlm.nih.gov/pubmed/34998903
http://dx.doi.org/10.1016/j.bmcl.2022.128526

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