An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury

Axons in the adult mammalian central nervous system fail to regenerate after spinal cord injury. Neurons lose their capacity to regenerate during development, but the intracellular processes underlying this loss are unclear. We found that critical components of the presynaptic active zone prevent ax...

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Detalles Bibliográficos
Autores principales: Hilton, Brett J., Husch, Andreas, Schaffran, Barbara, Lin, Tien-chen, Burnside, Emily R., Dupraz, Sebastian, Schelski, Max, Kim, Jisoo, Müller, Johannes Alexander, Schoch, Susanne, Imig, Cordelia, Brose, Nils, Bradke, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730507/
https://www.ncbi.nlm.nih.gov/pubmed/34706221
http://dx.doi.org/10.1016/j.neuron.2021.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730507/
https://www.ncbi.nlm.nih.gov/pubmed/34706221
http://dx.doi.org/10.1016/j.neuron.2021.10.007

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