A versatile and robust cell purification system with an RNA-only circuit composed of microRNA-responsive ON and OFF switches

Human induced pluripotent stem cells (iPSCs) are promising cell resources for cell therapy and drug discovery. However, iPSC-derived differentiated cells are often heterogenous and need purification using a flow cytometer, which has high cost and time consumption for large-scale purification. MicroR...

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Detalles Bibliográficos
Autores principales: Fujita, Yoshihiko, Hirosawa, Moe, Hayashi, Karin, Hatani, Takeshi, Yoshida, Yoshinori, Yamamoto, Takuya, Saito, Hirohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730616/
https://www.ncbi.nlm.nih.gov/pubmed/34985961
http://dx.doi.org/10.1126/sciadv.abj1793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730616/
https://www.ncbi.nlm.nih.gov/pubmed/34985961
http://dx.doi.org/10.1126/sciadv.abj1793

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