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Hybridization chain reaction circuit-based electrochemiluminescent biosensor for SARS-cov-2 RdRp gene assay

In this work, we designed an ECL ratiometric biosensor with a three-stranded Y-type DNA (Y-DNA) probe and induced a hybridization chain reaction (HCR) for the highly sensitive detection of SARS-CoV-2 nucleic acid. The important component of this system is the self-assembled Y-Shaped probe based on t...

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Detalles Bibliográficos
Autores principales: Zhang, Kai, Fan, Zhenqiang, Huang, Yue, Ding, Yuedi, Xie, Minhao, Wang, Minghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730713/
https://www.ncbi.nlm.nih.gov/pubmed/34998144
http://dx.doi.org/10.1016/j.talanta.2022.123207