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Hyaluronic acid fuels pancreatic cancer cell growth

Rewired metabolism is a hallmark of pancreatic ductal adenocarcinomas (PDA). Previously, we demonstrated that PDA cells enhance glycosylation precursor biogenesis through the hexosamine biosynthetic pathway (HBP) via activation of the rate limiting enzyme, glutamine-fructose 6-phosphate amidotransfe...

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Detalles Bibliográficos
Autores principales: Kim, Peter K, Halbrook, Christopher J, Kerk, Samuel A, Radyk, Megan, Wisner, Stephanie, Kremer, Daniel M, Sajjakulnukit, Peter, Andren, Anthony, Hou, Sean W, Trivedi, Ayush, Thurston, Galloway, Anand, Abhinav, Yan, Liang, Salamanca-Cardona, Lucia, Welling, Samuel D, Zhang, Li, Pratt, Matthew R, Keshari, Kayvan R, Ying, Haoqiang, Lyssiotis, Costas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730721/
https://www.ncbi.nlm.nih.gov/pubmed/34951587
http://dx.doi.org/10.7554/eLife.62645