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Hyaluronic acid fuels pancreatic cancer cell growth
Rewired metabolism is a hallmark of pancreatic ductal adenocarcinomas (PDA). Previously, we demonstrated that PDA cells enhance glycosylation precursor biogenesis through the hexosamine biosynthetic pathway (HBP) via activation of the rate limiting enzyme, glutamine-fructose 6-phosphate amidotransfe...
Autores principales: | Kim, Peter K, Halbrook, Christopher J, Kerk, Samuel A, Radyk, Megan, Wisner, Stephanie, Kremer, Daniel M, Sajjakulnukit, Peter, Andren, Anthony, Hou, Sean W, Trivedi, Ayush, Thurston, Galloway, Anand, Abhinav, Yan, Liang, Salamanca-Cardona, Lucia, Welling, Samuel D, Zhang, Li, Pratt, Matthew R, Keshari, Kayvan R, Ying, Haoqiang, Lyssiotis, Costas A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730721/ https://www.ncbi.nlm.nih.gov/pubmed/34951587 http://dx.doi.org/10.7554/eLife.62645 |
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