Cargando…

Selective blood-brain barrier permeabilization of brain metastases by a type 1 receptor-selective tumor necrosis factor mutein

BACKGROUND: Metastasis to the brain is a major challenge with poor prognosis. The blood-brain barrier (BBB) is a significant impediment to effective treatment, being intact during the early stages of tumor development and heterogeneously permeable at later stages. Intravenous injection of tumor necr...

Descripción completa

Detalles Bibliográficos
Autores principales: Munoz Pinto, Mario F, Campbell, Sandra J, Simoglou Karali, Christina, Johanssen, Vanessa A, Bristow, Claire, Cheng, Vinton W T, Zarghami, Niloufar, Larkin, James R, Pannell, Maria, Hearn, Arron, Chui, Cherry, Brinquis Nunez, Barbara, Bokma, Evert, Holgate, Robert, Anthony, Daniel C, Sibson, Nicola R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730757/
https://www.ncbi.nlm.nih.gov/pubmed/34297105
http://dx.doi.org/10.1093/neuonc/noab177