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Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse

BACKGROUND: Less than 5% of medulloblastoma (MB) patients survive following failure of contemporary radiation-based therapies. Understanding the molecular drivers of medulloblastoma relapse (rMB) will be essential to improve outcomes. Initial genome-wide investigations have suggested significant gen...

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Detalles Bibliográficos
Autores principales: Richardson, Stacey, Hill, Rebecca M, Kui, Christopher, Lindsey, Janet C, Grabovksa, Yura, Keeling, Claire, Pease, Louise, Bashton, Matthew, Crosier, Stephen, Vinci, Maria, André, Nicolas, Figarella-Branger, Dominique, Hansford, Jordan R, Lastowska, Maria, Zakrzewski, Krzysztof, Jorgensen, Mette, Pickles, Jessica C, Taylor, Michael D, Pfister, Stefan M, Wharton, Stephen B, Pizer, Barry, Michalski, Antony, Joshi, Abhijit, Jacques, Thomas S, Hicks, Debbie, Schwalbe, Edward C, Williamson, Daniel, Ramaswamy, Vijay, Bailey, Simon, Clifford, Steven C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730763/
https://www.ncbi.nlm.nih.gov/pubmed/34272868
http://dx.doi.org/10.1093/neuonc/noab178