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Environmental and sex-specific molecular signatures of glioma causation

BACKGROUND: The relative importance of genetic and environmental risk factors in gliomagenesis remains uncertain. METHODS: Using whole-exome sequencing data from 1105 adult gliomas, we evaluate the relative contribution to cancer cell lineage proliferation and survival of single-nucleotide mutations...

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Detalles Bibliográficos
Autores principales: Claus, Elizabeth B, Cannataro, Vincent L, Gaffney, Stephen G, Townsend, Jeffrey P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730771/
https://www.ncbi.nlm.nih.gov/pubmed/33942853
http://dx.doi.org/10.1093/neuonc/noab103