Molecular dynamics simulations of the flexibility and inhibition of SARS-CoV-2 NSP 13 helicase

The helicase protein of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is both a good potential drug target and very flexible. The flexibility, and therefore its function, could be reduced through knowledge of these motions and identification of allosteric pockets. Using molecular...

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Detalles Bibliográficos
Autores principales: Raubenolt, Bryan A., Islam, Naeyma N., Summa, Christoper M., Rick, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730789/
https://www.ncbi.nlm.nih.gov/pubmed/35021142
http://dx.doi.org/10.1016/j.jmgm.2022.108122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730789/
https://www.ncbi.nlm.nih.gov/pubmed/35021142
http://dx.doi.org/10.1016/j.jmgm.2022.108122

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