Antibody secreting cells are critically dependent on integrin α4β7/MAdCAM-1 for intestinal recruitment and control of the microbiota during chronic colitis

T and B cells employ integrin α4β7 to migrate to intestine under homeostatic conditions. Whether those cells differentially rely on α4β7 for homing during inflammatory conditions has not been fully examined. This may have implications for our understanding of the mode of action of anti-integrin ther...

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Detalles Bibliográficos
Autores principales: Tyler, Christopher J., Guzman, Mauricio, Lundborg, Luke R., Yeasmin, Shaila, Zgajnar, Nadia, Jedlicka, Paul, Bamias, Giorgos, Rivera-Nieves, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732264/
https://www.ncbi.nlm.nih.gov/pubmed/34433904
http://dx.doi.org/10.1038/s41385-021-00445-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732264/
https://www.ncbi.nlm.nih.gov/pubmed/34433904
http://dx.doi.org/10.1038/s41385-021-00445-z

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