Platycodin D inhibits autophagy and increases glioblastoma cell death via LDLR upregulation

Targeting autophagy is a promising therapeutic approach in cancer therapy. Here, we screened 30 traditional herbal medicines to identify novel autophagy regulators and found that Platycodon grandiflorus (PG) and platycodin D (PD), a triterpenoid saponin from PG, inhibited autophagy in glioblastoma m...

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Detalles Bibliográficos
Autores principales: Lee, Sol Ji, Choi, Yu‐Jeong, Kim, Hyo In, Moon, Hyo Eun, Paek, Sun Ha, Kim, Tai Young, Ko, Seong‐Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732342/
https://www.ncbi.nlm.nih.gov/pubmed/33931944
http://dx.doi.org/10.1002/1878-0261.12966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732342/
https://www.ncbi.nlm.nih.gov/pubmed/33931944
http://dx.doi.org/10.1002/1878-0261.12966

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