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Extracellular CIRP Induces Macrophage Extracellular Trap Formation Via Gasdermin D Activation

Extracellular cold-inducible RNA-binding protein (eCIRP) is a damage-associated molecular pattern promoting inflammation and tissue injury. During bacterial or viral infection, macrophages release DNA decorated with nuclear and cytoplasmic proteins known as macrophage extracellular traps (METs). Gas...

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Detalles Bibliográficos
Autores principales: Lee, Yongchan, Reilly, Bridgette, Tan, Chuyi, Wang, Ping, Aziz, Monowar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732379/
https://www.ncbi.nlm.nih.gov/pubmed/35003095
http://dx.doi.org/10.3389/fimmu.2021.780210