Glycoprotein Targeted CAR-NK Cells for the Treatment of SARS-CoV-2 Infection

H84T-Banana Lectin (BanLec) CAR-NK cells bind high mannose glycosites that decorate the SARS-CoV-2 envelope, thereby decreasing cellular infection in a model of SARS-CoV-2. H84T-BanLec CAR-NK cells are innate effector cells, activated by virus. This novel cellular agent is a promising therapeutic, c...

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Detalles Bibliográficos
Autores principales: Christodoulou, Ilias, Rahnama, Ruyan, Ravich, Jonas W., Seo, Jaesung, Zolov, Sergey N., Marple, Andrew N., Markovitz, David M., Bonifant, Challice L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732772/
https://www.ncbi.nlm.nih.gov/pubmed/35003077
http://dx.doi.org/10.3389/fimmu.2021.763460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732772/
https://www.ncbi.nlm.nih.gov/pubmed/35003077
http://dx.doi.org/10.3389/fimmu.2021.763460

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