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Continuous direct compression: Development of an empirical predictive model and challenges regarding PAT implementation

In this study, an empirical predictive model was developed based on the quantitative relationships between blend properties, critical quality attributes (CQA) and critical process parameters (CPP) related to blending and tableting. The blend uniformity and API concentration in the tablets were used...

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Detalles Bibliográficos
Autores principales: Bekaert, B., Van Snick, B., Pandelaere, K., Dhondt, J., Di Pretoro, G., De Beer, T., Vervaet, C., Vanhoorne, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732775/
https://www.ncbi.nlm.nih.gov/pubmed/35024605
http://dx.doi.org/10.1016/j.ijpx.2021.100110