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Human telomerase reverse transcriptase promotes the epithelial to mesenchymal transition in lung cancer cells by enhancing c-MET upregulation

Human telomerase reverse transcriptase (hTERT), the essential catalytic subunit of telomerase, is associated with telomere homeostasis to prevent replicative senescence and cellular aging. However, hTERT reactivation also has been linked to the acquisition of several hallmarks of cancer, although th...

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Detalles Bibliográficos
Autores principales: Prasad, Ram Raj, Mishra, Deepak Kumar, Kumar, Manoj, Yadava, Pramod Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732784/
https://www.ncbi.nlm.nih.gov/pubmed/35024489
http://dx.doi.org/10.1016/j.heliyon.2021.e08673