Orai1α, but not Orai1β, co-localizes with TRPC1 and is required for its plasma membrane location and activation in HeLa cells

The identification of two variants of the canonical pore-forming subunit of the Ca(2+) release-activated Ca(2+) (CRAC) channel Orai1, Orai1α and Orai1β, in mammalian cells arises the question whether they exhibit different functional characteristics. Orai1α and Orai1β differ in the N-terminal 63 ami...

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Detalles Bibliográficos
Autores principales: Sanchez-Collado, Jose, Lopez, Jose J., Jardin, Isaac, Berna-Erro, Alejandro, Camello, Pedro J., Cantonero, Carlos, Smani, Tarik, Salido, Gines M., Rosado, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732813/
https://www.ncbi.nlm.nih.gov/pubmed/34988680
http://dx.doi.org/10.1007/s00018-021-04098-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732813/
https://www.ncbi.nlm.nih.gov/pubmed/34988680
http://dx.doi.org/10.1007/s00018-021-04098-w

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