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Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells

BACKGROUND: Tumour progression relies on the ability of cancer cells to penetrate and invade neighbouring tissues. E-cadherin loss is associated with increased cell invasion in gastric carcinoma, and germline mutations of the E-cadherin gene are causative of hereditary diffuse gastric cancer. Althou...

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Detalles Bibliográficos
Autores principales: Figueiredo, Joana, Ferreira, Rui M., Xu, Han, Gonçalves, Margarida, Barros-Carvalho, André, Cravo, Janine, Maia, André F., Carneiro, Patrícia, Figueiredo, Céu, Smith, Michael L., Stamenović, Dimitrije, Morais-de-Sá, Eurico, Seruca, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732838/
https://www.ncbi.nlm.nih.gov/pubmed/34486077
http://dx.doi.org/10.1007/s10120-021-01239-9