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Relationship Between Changes in Serum Levels of Intact Parathyroid Hormone and Sclerostin After a Single Dose of Zoledronic Acid: Results of a Phase 1 Pharmacokinetic Study

Although changes in serum sclerostin levels at 12 months after infusion of zoledronic acid have been reported, the changes in sclerostin levels at earlier time points are poorly understood. We reanalyzed the study data of a previous phase 1 pharmacokinetic study and investigated the correlation betw...

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Detalles Bibliográficos
Autores principales: Kuroda, Tatsuhiko, Shiraki, Masataka, Nakamura, Toshitaka, Suzuki, Hiroaki, Hiraishi, Kazuki, Sugimoto, Toshitsugu, Tanaka, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732852/
https://www.ncbi.nlm.nih.gov/pubmed/34427705
http://dx.doi.org/10.1007/s00223-021-00900-w