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Colorectal cancer promoter methylation alteration affects the expression of glutamate ionotropic receptor AMPA type subunit 4 alternative isoforms potentially relevant in colon tissue

DNA methylation alterations are early events during tumourigenesis, affecting genes involved in the crosstalk between cells and surroundings in colorectal cancer (CRC). Among these genes, GRIA4, Glutamate Ionotropic Receptor AMPA Type Subunit 4, displays hypermethylation in the promoter region, and...

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Detalles Bibliográficos
Autores principales: Vega-Benedetti, Ana Florencia, Loi, Eleonora, Moi, Loredana, Restivo, Angelo, Cabras, Francesco, Deidda, Simona, Pretta, Andrea, Ziranu, Pina, Orrù, Sandra, Scartozzi, Mario, Zorcolo, Luigi, Zavattari, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732896/
https://www.ncbi.nlm.nih.gov/pubmed/34719006
http://dx.doi.org/10.1007/s13577-021-00640-x