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DNA methylation-based classification of malformations of cortical development in the human brain

Malformations of cortical development (MCD) comprise a broad spectrum of structural brain lesions frequently associated with epilepsy. Disease definition and diagnosis remain challenging and are often prone to arbitrary judgment. Molecular classification of histopathological entities may help ration...

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Detalles Bibliográficos
Autores principales: Jabari, Samir, Kobow, Katja, Pieper, Tom, Hartlieb, Till, Kudernatsch, Manfred, Polster, Tilman, Bien, Christian G., Kalbhenn, Thilo, Simon, Matthias, Hamer, Hajo, Rössler, Karl, Feucht, Martha, Mühlebner, Angelika, Najm, Imad, Peixoto-Santos, José Eduardo, Gil-Nagel, Antonio, Delgado, Rafael Toledano, Aledo-Serrano, Angel, Hou, Yanghao, Coras, Roland, von Deimling, Andreas, Blümcke, Ingmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732912/
https://www.ncbi.nlm.nih.gov/pubmed/34797422
http://dx.doi.org/10.1007/s00401-021-02386-0