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Single Nucleotide Polymorphisms in the Bovine TLR2 Extracellular Domain Contribute to Breed and Species-Specific Innate Immune Functionality

Recent evidence suggests that several cattle breeds may be more resistant to infection with the zoonotic pathogen Mycobacterium bovis. Our data presented here suggests that the response to mycobacterial antigens varies in macrophages generated from Brown Swiss (BS) and Holstein Friesian (HF) cattle,...

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Detalles Bibliográficos
Autores principales: Bartens, Marie-Christine, Gibson, Amanda J., Etherington, Graham J., Di Palma, Federica, Holder, Angela, Werling, Dirk, Willcocks, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732954/
https://www.ncbi.nlm.nih.gov/pubmed/35003078
http://dx.doi.org/10.3389/fimmu.2021.764390