Diverse human astrocyte and microglial transcriptional responses to Alzheimer’s pathology

To better define roles that astrocytes and microglia play in Alzheimer’s disease (AD), we used single-nuclei RNA-sequencing to comprehensively characterise transcriptomes in astrocyte and microglia nuclei selectively enriched during isolation post-mortem from neuropathologically defined AD and contr...

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Detalles Bibliográficos
Autores principales: Smith, Amy M., Davey, Karen, Tsartsalis, Stergios, Khozoie, Combiz, Fancy, Nurun, Tang, See Swee, Liaptsi, Eirini, Weinert, Maria, McGarry, Aisling, Muirhead, Robert C. J., Gentleman, Steve, Owen, David R., Matthews, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732962/
https://www.ncbi.nlm.nih.gov/pubmed/34767070
http://dx.doi.org/10.1007/s00401-021-02372-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732962/
https://www.ncbi.nlm.nih.gov/pubmed/34767070
http://dx.doi.org/10.1007/s00401-021-02372-6

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