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Induction of Peptide-specific CTL Activity and Inhibition of Tumor Growth Following Immunization with Nanoparticles Coated with Tumor Peptide-MHC-I Complexes

Tumor peptides associated with MHC class I molecules or their synthetic variants have attracted great attention for their potential use as vaccines to induce tumor-specific CTLs. However, the outcome of clinical trials of peptide-based tumor vaccines has been disappointing. There are various reasons...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Hyun, Park, Ha-Eun, Jeong, Seong-Un, Moon, Jun-Hyeok, Lee, Young-Ran, Kim, Jeong-Ki, Kong, Hyunseok, Park, Chan-Su, Lee, Chong-Kil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733191/
https://www.ncbi.nlm.nih.gov/pubmed/35036031
http://dx.doi.org/10.4110/in.2021.21.e44