Proteinopathies as Hallmarks of Impaired Gene Expression, Proteostasis and Mitochondrial Function in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons. As with the majority of neurodegenerative diseases, the pathological hallmarks of ALS involve proteinopathies which lead to the formation o...

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Detalles Bibliográficos
Autores principales: Benson, Bridget C., Shaw, Pamela J., Azzouz, Mimoun, Highley, J. Robin, Hautbergue, Guillaume M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733206/
https://www.ncbi.nlm.nih.gov/pubmed/35002606
http://dx.doi.org/10.3389/fnins.2021.783624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733206/
https://www.ncbi.nlm.nih.gov/pubmed/35002606
http://dx.doi.org/10.3389/fnins.2021.783624

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