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The mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals

BACKGROUND: Oogenesis is a fundamental process of human reproduction, and mitochondria play crucial roles in oocyte competence. Mitochondrial ATP-dependent Lon protease 1 (LONP1) functions as a critical protein in maintaining mitochondrial and cellular homeostasis in somatic cells. However, the esse...

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Detalles Bibliográficos
Autores principales: Sheng, Xiaoqiang, Liu, Chuanming, Yan, Guijun, Li, Guangyu, Liu, Jingyu, Yang, Yanjun, Li, Shiyuan, Li, Zhongxun, Zhou, Jidong, Zhen, Xin, Zhang, Yang, Diao, Zhenyu, Hu, Yali, Fu, Chuanhai, Yao, Bin, Li, Chaojun, Cao, Yu, Lu, Bin, Yang, Zhongzhou, Qin, Yingying, Sun, Haixiang, Ding, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733232/
https://www.ncbi.nlm.nih.gov/pubmed/34974310
http://dx.doi.org/10.1016/j.ebiom.2021.103790