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The deubiquitinase USP28 stabilizes the expression of RecQ family helicases and maintains the viability of triple negative breast cancer cells

Triple-negative breast cancer (TNBC) lacks significant expression of the estrogen receptor, the progesterone receptor, and of human epidermal growth factor receptor. It is the most aggressive and malignant of all breast cancers, and for which, there are currently no effective targeted therapies. We...

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Detalles Bibliográficos
Autores principales: Wang, Jiewei, Dong, Yiping, Ma, Huailu, Wu, Lingzhi, Zhen, Xinghua, Tang, Lichun, Jin, Jianping, Han, Suxia, Zhang, Pumin, Peng, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733264/
https://www.ncbi.nlm.nih.gov/pubmed/34822842
http://dx.doi.org/10.1016/j.jbc.2021.101443