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Pancreatic Cancer Patient-Derived Organoid Platforms: A Clinical Tool to Study Cell- and Non-Cell-Autonomous Mechanisms of Treatment Response

For many years, cell lines and animal models have been essential to improve our understanding of the basis of cell metabolism, signaling, and genetics. They also provided an essential boost to cancer drug discovery. Nevertheless, these model systems failed to reproduce the tumor heterogeneity and th...

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Detalles Bibliográficos
Autores principales: Piro, Geny, Agostini, Antonio, Larghi, Alberto, Quero, Giuseppe, Carbone, Carmine, Esposito, Annachiara, Rizzatti, Gianenrico, Attili, Fabia, Alfieri, Sergio, Costamagna, Guido, Tortora, Giampaolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733292/
https://www.ncbi.nlm.nih.gov/pubmed/35004765
http://dx.doi.org/10.3389/fmed.2021.793144