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Blood pressure and cognitive function among older adults in India

OBJECTIVE: We aimed to investigate the relationship between blood pressure and cognitive function among older adults in India. METHODS: In this study, we analyzed cross-sectional data of systolic and diastolic blood pressure (SBP and DBP, respectively) and cognitive testing from 3690 adults aged 60...

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Autores principales: Farron, Madeline R., Kabeto, Mohammed U., Levine, Deborah A., Wixom, Caroline R., Langa, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733366/
http://dx.doi.org/10.1177/03000605211068720
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author Farron, Madeline R.
Kabeto, Mohammed U.
Levine, Deborah A.
Wixom, Caroline R.
Langa, Kenneth M.
author_facet Farron, Madeline R.
Kabeto, Mohammed U.
Levine, Deborah A.
Wixom, Caroline R.
Langa, Kenneth M.
author_sort Farron, Madeline R.
collection PubMed
description OBJECTIVE: We aimed to investigate the relationship between blood pressure and cognitive function among older adults in India. METHODS: In this study, we analyzed cross-sectional data of systolic and diastolic blood pressure (SBP and DBP, respectively) and cognitive testing from 3690 adults aged 60 years and older participating in the Longitudinal Aging Study in India—Diagnostic Assessment of Dementia from 14 states in India. RESULTS: After controlling for key sociodemographic, health, and geographic factors, higher SBP and lower DBP were each independently associated with worse cognitive function. Older age, female sex, lower education level, being widowed, residing in a rural area, being a member of a Scheduled Caste or Scheduled Tribe, having a low level of economic consumption, being underweight, and a history of stroke were all independently associated with worse cognitive function scores. CONCLUSIONS: Both SBP and DBP were independently associated with cognitive function among older adults in India in diverging directions. Clinical interventions targeting high SBP and low DBP may benefit both cognitive health and cardiovascular health.
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spelling pubmed-87333662022-01-07 Blood pressure and cognitive function among older adults in India Farron, Madeline R. Kabeto, Mohammed U. Levine, Deborah A. Wixom, Caroline R. Langa, Kenneth M. J Int Med Res Retrospective Clinical Research Report OBJECTIVE: We aimed to investigate the relationship between blood pressure and cognitive function among older adults in India. METHODS: In this study, we analyzed cross-sectional data of systolic and diastolic blood pressure (SBP and DBP, respectively) and cognitive testing from 3690 adults aged 60 years and older participating in the Longitudinal Aging Study in India—Diagnostic Assessment of Dementia from 14 states in India. RESULTS: After controlling for key sociodemographic, health, and geographic factors, higher SBP and lower DBP were each independently associated with worse cognitive function. Older age, female sex, lower education level, being widowed, residing in a rural area, being a member of a Scheduled Caste or Scheduled Tribe, having a low level of economic consumption, being underweight, and a history of stroke were all independently associated with worse cognitive function scores. CONCLUSIONS: Both SBP and DBP were independently associated with cognitive function among older adults in India in diverging directions. Clinical interventions targeting high SBP and low DBP may benefit both cognitive health and cardiovascular health. SAGE Publications 2022-01-04 /pmc/articles/PMC8733366/ http://dx.doi.org/10.1177/03000605211068720 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Retrospective Clinical Research Report
Farron, Madeline R.
Kabeto, Mohammed U.
Levine, Deborah A.
Wixom, Caroline R.
Langa, Kenneth M.
Blood pressure and cognitive function among older adults in India
title Blood pressure and cognitive function among older adults in India
title_full Blood pressure and cognitive function among older adults in India
title_fullStr Blood pressure and cognitive function among older adults in India
title_full_unstemmed Blood pressure and cognitive function among older adults in India
title_short Blood pressure and cognitive function among older adults in India
title_sort blood pressure and cognitive function among older adults in india
topic Retrospective Clinical Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733366/
http://dx.doi.org/10.1177/03000605211068720
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