Novel Opipramol-Baclofen Combination Alleviates Depression and Craving and Facilitates Recovery From Substance Use Disorder—An Animal Model and a Human Study

Substance use disorders (SUDs) are associated with depression and anxiety, with the latter being one of the major factors in substance-seeking and relapse. Due to dose-dependent sedative side effects there is limited efficacy of baclofen treatment for SUDs. Here we suggest the use of a novel combina...

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Detalles Bibliográficos
Autores principales: Bareli, Tzofnat, Ahdoot, Hadas Levi, Ben Moshe, Hila, Barnea, Royi, Warhaftig, Gal, Gispan, Iris, Maayan, Rachel, Rosca, Paola, Weizman, Abraham, Yadid, Gal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Behavioral Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733380/
https://www.ncbi.nlm.nih.gov/pubmed/35002647
http://dx.doi.org/10.3389/fnbeh.2021.788708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733380/
https://www.ncbi.nlm.nih.gov/pubmed/35002647
http://dx.doi.org/10.3389/fnbeh.2021.788708

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