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Hormone Replacement Therapy Reverses Gut Microbiome and Serum Metabolome Alterations in Premature Ovarian Insufficiency

OBJECTIVE: We explored the gut microbiome and serum metabolome alterations in patients with premature ovarian insufficiency (POI) and the effects of hormone replacement therapy (HRT) with the aim to unravel the pathological mechanism underlying POI. METHODS: Fecal and serum samples obtained from hea...

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Detalles Bibliográficos
Autores principales: Jiang, Lingling, Fei, Haiyi, Tong, Jinfei, Zhou, Jiena, Zhu, Jiajuan, Jin, Xiaoying, Shi, Zhan, Zhou, Yan, Ma, Xudong, Yu, Hailan, Yang, Jianhua, Zhang, Songying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733385/
https://www.ncbi.nlm.nih.gov/pubmed/35002971
http://dx.doi.org/10.3389/fendo.2021.794496