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Transmission distortion and genetic incompatibilities between alleles in a multigenerational mouse advanced intercross line

While direct additive and dominance effects on complex traits have been mapped repeatedly, additional genetic factors contributing to the heterogeneity of complex traits have been scarcely investigated. To assess genetic background effects, we investigated transmission ratio distortions (TRDs) of al...

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Detalles Bibliográficos
Autores principales: Arends, Danny, Kärst, Stefan, Heise, Sebastian, Korkuc, Paula, Hesse, Deike, Brockmann, Gudrun A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733443/
https://www.ncbi.nlm.nih.gov/pubmed/34791189
http://dx.doi.org/10.1093/genetics/iyab192