MiR-526b-3p Attenuates Breast Cancer Stem Cell Properties and Chemoresistance by Targeting HIF-2α/Notch Signaling

Chemoresistance is a severe clinical challenge in breast cancer. Hypoxia and cancer stem cells (CSCs) contribute to the paclitaxel (PTX) resistance, but the molecular mechanisms are still elusive. MicorRNAs (miRNA) have been considered a promising therapeutic strategy in various cancers. Here, we id...

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Detalles Bibliográficos
Autores principales: Liu, Jing-Hua, Li, Wen-Ting, Yang, Yue, Qi, Yan-Bo, Cheng, Yu, Wu, Jia-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733566/
https://www.ncbi.nlm.nih.gov/pubmed/35004266
http://dx.doi.org/10.3389/fonc.2021.696269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733566/
https://www.ncbi.nlm.nih.gov/pubmed/35004266
http://dx.doi.org/10.3389/fonc.2021.696269

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