Phosphatidylinositol-4,5-Bisphosphate Binding to Amphiphysin-II Modulates T-Tubule Remodeling: Implications for Heart Failure

BIN1 (amphyphysin-II) is a structural protein involved in T-tubule (TT) formation and phosphatidylinositol-4,5-bisphosphate (PIP2) is responsible for localization of BIN1 to sarcolemma. The goal of this study was to determine if PIP2-mediated targeting of BIN1 to sarcolemma is compromised during the...

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Detalles Bibliográficos
Autores principales: Zhou, Junlan, Singh, Neha, Monnier, Chloe, Marszalec, William, Gao, Li, Jin, Jing, Frisk, Michael, Louch, William E., Verma, Suresh, Krishnamurthy, Prasanna, Nico, Elsa, Mulla, Maaz, Aistrup, Gary L., Kishore, Raj, Wasserstrom, J. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733645/
https://www.ncbi.nlm.nih.gov/pubmed/35002765
http://dx.doi.org/10.3389/fphys.2021.782767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733645/
https://www.ncbi.nlm.nih.gov/pubmed/35002765
http://dx.doi.org/10.3389/fphys.2021.782767

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