Tumor-Derived Extracellular Vesicles Induce Abnormal Angiogenesis via TRPV4 Downregulation and Subsequent Activation of YAP and VEGFR2

Tumor angiogenesis is initiated and maintained by the tumor microenvironment through secretion of autocrine and paracrine factors, including extracellular vesicles (EVs). Although tumor-derived EVs (t-EVs) have been implicated in tumor angiogenesis, growth and metastasis, most studies on t-EVs are f...

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Detalles Bibliográficos
Autores principales: Guarino, Brianna, Katari, Venkatesh, Adapala, Ravi, Bhavnani, Neha, Dougherty, Julie, Khan, Mahmood, Paruchuri, Sailaja, Thodeti, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733651/
https://www.ncbi.nlm.nih.gov/pubmed/35004649
http://dx.doi.org/10.3389/fbioe.2021.790489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733651/
https://www.ncbi.nlm.nih.gov/pubmed/35004649
http://dx.doi.org/10.3389/fbioe.2021.790489

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