Abnormal Flow Conditions Promote Endocardial Fibroelastosis Via Endothelial-to-Mesenchymal Transition, Which Is Responsive to Losartan Treatment

Endocardial fibroelastosis (EFE) is defined by fibrotic tissue on the endocardium and forms partly through aberrant endothelial-to-mesenchymal transition. However, the pathologic triggers are still unknown. In this study, we showed that abnormal flow induces EFE partly through endothelial-to-mesench...

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Detalles Bibliográficos
Autores principales: Oh, Nicholas A., Hong, Xuechong, Doulamis, Ilias P., Meibalan, Elamaran, Peiseler, Teresa, Melero-Martin, Juan, García-Cardeña, Guillermo, del Nido, Pedro J., Friehs, Ingeborg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Preclinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733675/
https://www.ncbi.nlm.nih.gov/pubmed/35024504
http://dx.doi.org/10.1016/j.jacbts.2021.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733675/
https://www.ncbi.nlm.nih.gov/pubmed/35024504
http://dx.doi.org/10.1016/j.jacbts.2021.10.002

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