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Lipids and Phosphorylation Conjointly Modulate Complex Formation of β(2)-Adrenergic Receptor and β-arrestin2
G protein-coupled receptors (GPCRs) are the largest class of human membrane proteins that bind extracellular ligands at their orthosteric binding pocket to transmit signals to the cell interior. Ligand binding evokes conformational changes in GPCRs that trigger the binding of intracellular interacti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733679/ https://www.ncbi.nlm.nih.gov/pubmed/35004696 http://dx.doi.org/10.3389/fcell.2021.807913 |