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WSV056 Inhibits Shrimp Nitric Oxide Synthase Activity by Downregulating Litopenaeus vannamei Sepiapterin Reductase to Promote White Spot Syndrome Virus Replication

Sepiapterin reductase (Spr) plays an essential role in the biosynthesis of tetrahydrobiopterin (BH4), a key cofactor of multiple enzymes involved in various physiological and immune processes. Suppression of Spr could result in BH4 deficiency-caused diseases in human and murine models. However, info...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Zheng, Qin, Yu, Chen, Pan, Changkun, Luo, Peng, Chen, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733705/
https://www.ncbi.nlm.nih.gov/pubmed/35003027
http://dx.doi.org/10.3389/fmicb.2021.796049