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Discovery of Mycothiogranaticins from Streptomyces vietnamensis GIMV4.0001 and the Regulatory Effect of Mycothiol on the Granaticin Biosynthesis

Granaticins are benzoisochromanequinone polyketides with remarkable antibacterial and anticancer activities. Three sulfur-containing granaticin congeners, mycothiogranaticins A (1), B (2) and granaticin MA (3) were discovered from a granaticin-producing strain of Streptomyces vietnamensis GIMV4.0001...

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Detalles Bibliográficos
Autores principales: Deng, Ming-Rong, Li, Yan, Luo, Xiao, Zheng, Xiang-Ling, Chen, Yuchan, Zhang, Yu-Lian, Zhang, Weimin, Zhou, Hao, Zhu, Honghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733708/
https://www.ncbi.nlm.nih.gov/pubmed/35004619
http://dx.doi.org/10.3389/fchem.2021.802279