Dioctanoyl Ultrashort Tetrabasic β-Peptides Sensitize Multidrug-Resistant Gram-Negative Bacteria to Novobiocin and Rifampicin

Recently reported peptidomimetics with increased resistance to trypsin were shown to sensitize priority multidrug-resistant (MDR) Gram-negative bacteria to novobiocin and rifampicin. To further optimize proteolytic stability, β-amino acid-containing derivatives of these compounds were prepared, resu...

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Detalles Bibliográficos
Autores principales: Ramirez, Danyel, Berry, Liam, Domalaon, Ronald, Li, Yanqi, Arthur, Gilbert, Kumar, Ayush, Schweizer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733726/
https://www.ncbi.nlm.nih.gov/pubmed/35003035
http://dx.doi.org/10.3389/fmicb.2021.803309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733726/
https://www.ncbi.nlm.nih.gov/pubmed/35003035
http://dx.doi.org/10.3389/fmicb.2021.803309

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