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Dioctanoyl Ultrashort Tetrabasic β-Peptides Sensitize Multidrug-Resistant Gram-Negative Bacteria to Novobiocin and Rifampicin
Recently reported peptidomimetics with increased resistance to trypsin were shown to sensitize priority multidrug-resistant (MDR) Gram-negative bacteria to novobiocin and rifampicin. To further optimize proteolytic stability, β-amino acid-containing derivatives of these compounds were prepared, resu...
Autores principales: | Ramirez, Danyel, Berry, Liam, Domalaon, Ronald, Li, Yanqi, Arthur, Gilbert, Kumar, Ayush, Schweizer, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733726/ https://www.ncbi.nlm.nih.gov/pubmed/35003035 http://dx.doi.org/10.3389/fmicb.2021.803309 |
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