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Update of the keratin gene family: evolution, tissue-specific expression patterns, and relevance to clinical disorders

Intermediate filament (IntFil) genes arose during early metazoan evolution, to provide mechanical support for plasma membranes contacting/interacting with other cells and the extracellular matrix. Keratin genes comprise the largest subset of IntFil genes. Whereas the first keratin gene appeared in s...

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Detalles Bibliográficos
Autores principales: Ho, Minh, Thompson, Brian, Fisk, Jeffrey Nicholas, Nebert, Daniel W., Bruford, Elspeth A., Vasiliou, Vasilis, Bunick, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733776/
https://www.ncbi.nlm.nih.gov/pubmed/34991727
http://dx.doi.org/10.1186/s40246-021-00374-9