Enhanced Contractive Tension and Upregulated Muscarinic Receptor 2/3 in Colorectum Contribute to Constipation in 6-Hydroxydopamine-Induced Parkinson’s Disease Rats

Constipation and defecatory dysfunctions are frequent symptoms in patients with Parkinson’s disease (PD). The pathology of Lewy bodies in colonic and rectal cholinergic neurons suggests that cholinergic pathways are involved in colorectal dysmotility in PD. However, the underlying mechanism is uncle...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Li, Zhang, Xiao-Hui, Yu, Xiao, Zheng, Li-Fei, Feng, Xiao-Yan, Liu, Chen-Zhe, Quan, Zhu-Sheng, Zhang, Yue, Zhu, Jin-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733788/
https://www.ncbi.nlm.nih.gov/pubmed/35002677
http://dx.doi.org/10.3389/fnagi.2021.770841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733788/
https://www.ncbi.nlm.nih.gov/pubmed/35002677
http://dx.doi.org/10.3389/fnagi.2021.770841

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