Cargando…

Enhanced Contractive Tension and Upregulated Muscarinic Receptor 2/3 in Colorectum Contribute to Constipation in 6-Hydroxydopamine-Induced Parkinson’s Disease Rats

Constipation and defecatory dysfunctions are frequent symptoms in patients with Parkinson’s disease (PD). The pathology of Lewy bodies in colonic and rectal cholinergic neurons suggests that cholinergic pathways are involved in colorectal dysmotility in PD. However, the underlying mechanism is uncle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiao-Li, Zhang, Xiao-Hui, Yu, Xiao, Zheng, Li-Fei, Feng, Xiao-Yan, Liu, Chen-Zhe, Quan, Zhu-Sheng, Zhang, Yue, Zhu, Jin-Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733788/ https://www.ncbi.nlm.nih.gov/pubmed/35002677 http://dx.doi.org/10.3389/fnagi.2021.770841

Ejemplares similares

New Understanding on the Pathophysiology and Treatment of Constipation in Parkinson’s Disease
por: Xu, Jianli, et al.
Publicado: (2022)

Clinical Characteristics of Minor Hallucinations in Chinese Parkinson's Disease Patients
por: Zhang, Yu, et al.
Publicado: (2022)

Pathogenic tau decreases nuclear tension in cultured neurons
por: Sohn, Claira, et al.
Publicado: (2023)

Microglial autophagy in Alzheimer’s disease and Parkinson’s disease
por: Wang, Zhifu, et al.
Publicado: (2023)

Upregulation of Cysteine Protease Cathepsin X in the 6-Hydroxydopamine Model of Parkinson’s Disease
por: Pišlar, Anja, et al.
Publicado: (2018)

Pentraxin 3 promotes the osteoblastic differentiation of MC3T3-E1 cells through the PI3K/Akt signaling pathway
por: Liu, Yong, et al.
Publicado: (2020)

Potential roles of oxidative distress on neurodegeneration in Parkinson's disease with neuropsychiatric symptoms
por: Li, Dan-ning, et al.
Publicado: (2022)

Topological patterns of motor networks in Parkinson’s disease with different sides of onset: A resting-state-informed structural connectome study
por: Zhang, Xiuli, et al.
Publicado: (2022)

L-Glutamine alleviates osteoarthritis by regulating lncRNA-NKILA expression through the TGF-β1/SMAD2/3 signalling pathway
por: Ma, Xiao, et al.
Publicado: (2022)

Application of Neurotoxin-Induced Animal Models in the Study of Parkinson’s Disease-Related Depression: Profile and Proposal
por: Mou, Ya-Kui, et al.
Publicado: (2022)

Efficacy of Tai Chi on lower limb function of Parkinson’s disease patients: A systematic review and meta-analysis
por: Zhu, Ping-an, et al.
Publicado: (2023)

Physiological and pathophysiological role of ion channels and transporters in the colorectum and colorectal cancer
por: Zhang, Minglin, et al.
Publicado: (2020)

Study on the characteristics of intestinal motility of constipation in patients with Parkinson's disease
por: Zhang, Mei, et al.
Publicado: (2021)

Sodium butyrate ameliorates gut dysfunction and motor deficits in a mouse model of Parkinson’s disease by regulating gut microbiota
por: Zhang, Yi, et al.
Publicado: (2023)

Effect of puerarin on action potential and sodium channel activation in human hypertrophic cardiomyocytes
por: Lin, Yu-hui, et al.
Publicado: (2020)

Evaluation of fecal microbiota transplantation in Parkinson's disease patients with constipation
por: Kuai, Xiao-yi, et al.
Publicado: (2021)

The role of microglial autophagy in Parkinson’s disease
por: Zhu, Rui, et al.
Publicado: (2022)

Factors Contributing to the Severity and Laterality of Pisa Syndrome in Parkinson’s Disease
por: Huh, Young Eun, et al.
Publicado: (2022)

Effectiveness of aerobic and resistance training on the motor symptoms in Parkinson's disease: Systematic review and network meta-analysis
por: Zhou, Xiao, et al.
Publicado: (2022)

Time-course behavioral features are correlated with Parkinson's disease-associated pathology in a 6-hydroxydopamine hemiparkinsonian rat model
por: Su, Rui-Jun, et al.
Publicado: (2018)

Altered local and remote functional connectivity in mild Alzheimer’s disease patients with sleep disturbances
por: Wang, Lei, et al.
Publicado: (2023)

Age-related somatic mutation burden in human tissues
por: Ren, Peijun, et al.
Publicado: (2022)

The Cortical and Striatal Gene Expression Profile of 100 Hz Electroacupuncture Treatment in 6-Hydroxydopamine-Induced Parkinson's Disease Model
por: Huo, Li-Rong, et al.
Publicado: (2012)

LncRNA SNHG6 knockdown inhibits cisplatin resistance and progression of gastric cancer through miR-1297/BCL-2 axis
por: Mei, Jiazhuan, et al.
Publicado: (2021)

G-quadruplexes Stabilization Upregulates CCN1 and Accelerates Aging in Cultured Cerebral Endothelial Cells
por: Noh, Brian, et al.
Publicado: (2022)

Differences in brain pathological changes between rotenone and 6-hydroxydopamine Parkinson’s disease models
por: Liu, Lan-Xiang, et al.
Publicado: (2018)

Whole exome sequencing identified a new compound heterozygous PRKN mutation in a Chinese family with early-onset Parkinson’s disease
por: Li, Tianbai, et al.
Publicado: (2020)

Enhanced brain functional connectivity and activation after 12-week Tai Chi-based action observation training in patients with Parkinson’s disease
por: Meng, Lin, et al.
Publicado: (2023)

Neuroprotective effects of insulin-like growth factor-2 in 6-hydroxydopamine-induced cellular and mouse models of Parkinson’s disease
por: Zhang, Hai-Ying, et al.
Publicado: (2022)

Profiling the low-beta characteristics of the subthalamic nucleus in early- and late-onset Parkinson’s disease
por: Wu, Delong, et al.
Publicado: (2023)

Depression Is Associated With Constipation in Patients With Parkinson's Disease
por: Xiao-ling, Qin, et al.
Publicado: (2020)

Serrated neoplasia in the colorectum: gut microbiota and molecular pathways
por: Kang, Xing, et al.
Publicado: (2020)

Replenishing the Aged Brains: Targeting Oligodendrocytes and Myelination?
por: Zhang, Xi, et al.
Publicado: (2021)

Analysis of gene expression profiles in Alzheimer’s disease patients with different lifespan: A bioinformatics study focusing on the disease heterogeneity
por: Zhang, Ji, et al.
Publicado: (2023)

Genetically Predicted Levels of Circulating Inflammatory Cytokines and the Risk and Age at Onset of Parkinson’s Disease: A Two-Sample Mendelian Randomization Study
por: Zhao, Yating, et al.
Publicado: (2022)

Effects of levodopa on gut bacterial antibiotic resistance in Parkinson’s disease rat
por: Sheng, Shuo, et al.
Publicado: (2023)

Inhibiting BDNF Signaling Upregulates Hippocampal H3K9me3 in a Manner Dependent On In Vitro Aging and Oxidative Stress
por: Ionescu-Tucker, Andra, et al.
Publicado: (2022)

Recognition of Freezing of Gait in Parkinson’s Disease Based on Machine Vision
por: Li, Wendan, et al.
Publicado: (2022)

Efficacy of Traditional Chinese Exercise in Improving Gait and Balance in Cases of Parkinson's Disease: A Systematic Review and Meta-analysis
por: Wu, Minmin, et al.
Publicado: (2022)

Somatic Mutations Detected in Parkinson Disease Could Affect Genes With a Role in Synaptic and Neuronal Processes
por: Lobon, Irene, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qfqncpg337rs230c4ecn4p6eo8