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The C. elegans mapping locus rol-9 is encoded by a gain-of-function mutation in mlt-11

We mapped rol-9 to the mlt-11 locus (encoded by the gene W01F3.3) on the far-right end of chromosome V. The canonical allele of rol-9, sc148, is an in-frame deletion in a conserved exon of the protein that creates a gain-of-function roller phenotype. sc148 deletes a short peptide of unknown function...

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Detalles Bibliográficos
Autores principales: Rich, Matthew S, Nix, Paola, Jorgensen, Erik M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733821/
https://www.ncbi.nlm.nih.gov/pubmed/35005481
http://dx.doi.org/10.17912/micropub.biology.000506