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Cyclin-Dependent Kinase Inhibitors and Their Therapeutic Potential in Colorectal Cancer Treatment

Cyclin-dependent kinases (CDKs) are key players in cell cycle regulation. So far, more than ten CDKs have been described. Their direct interaction with cyclins allow progression through G1 phase, transitions to S and G2 phase and finally through mitosis (M). While CDK activation is important in cell...

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Detalles Bibliográficos
Autores principales: Thoma, Oana-Maria, Neurath, Markus F., Waldner, Maximilian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733931/
https://www.ncbi.nlm.nih.gov/pubmed/35002699
http://dx.doi.org/10.3389/fphar.2021.757120