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Fluid shear stress and endothelial cells synergistically promote osteogenesis of mesenchymal stem cells via integrin β1-FAK-ERK1/2 pathway

Prevascularization and mechanical stimulation have been reported as effective methods for the construction of functional bone tissue. However, their combined effects on osteogenic differentiation and its mechanism remain to be explored. Here, the effects of fluid shear stress (FSS) on osteogenic dif...

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Detalles Bibliográficos
Autores principales: JIANG, Mingli, SHEN, Qihua, ZHOU, Yi, REN, Wenxia, CHAI, Miaomiao, ZHOU, Yan, TAN, Wen-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733951/
https://www.ncbi.nlm.nih.gov/pubmed/35068949
http://dx.doi.org/10.3906/biy-2104-20